ASSESS THE PREVALENCE OF RESPIRATORY PROBLEM AND KNOWLEDGE ON HEALTH EFFECTS OF PEOPLE RESIDING NEAR QUARRY

Objective: In the quarry area, there are various suspended particulate matters are mixed with the ambient air in and around. People residing near to that quarry areas are exposed to hazards through the inhalation of airborne particulates. Due to that, the respiratory problems are very common among them. The study was aimed to assess the prevalence of respiratory problems and determine the level of knowledge on health effects of people living near to quarry at Kundrathur.Methods: Descriptive cross-sectional research design was adopted. Convenient sampling technique was used to select 60 people residing near the quarry. The data was collected by using structured questionnaire through face to face interview. The collected data was organised and analysed by descriptive and inferential statistics.Results: The study findings showed that the prevalence of respiratory problems was high 41(68.33%) among people residing near the quarry and 19(31.66%) people did not show any signs and symptoms of respiratory problems. The knowledge regarding health effects was showing that 39(65%) people had inadequate knowledge, 21(35%) people had the moderate knowledge, and none of the people had adequate knowledge.Conclusion: The study concluded that, though there was the prevalence of respiratory problems and most of them had inadequate knowledge on health effects and there is a need to advise the people about safety from respiratory diseases

Automated object detection of mechanical fasteners using faster region based convolutional neural networks

Mechanical fasteners are widely used in manufacturing of hardware and mechanical components such as automobiles, turbine & power generation and industries. Object detection method play a vital role to make a smart system for the society. Internet of things (IoT) leads to automation based on sensors and actuators not enough to build the systems due to limitations of sensors. Computer vision is the one which makes IoT too much smarter using deep learning techniques. Object detection is used to detect, recognize and localize the object in an image or a real time video. In industry revolution, robot arm is used to fit the fasteners to the automobile components. This system will helps the robot to detect the object of fasteners such as screw and nails accordingly to fit to the vehicle moved in the assembly line. Faster R-CNN deep learning algorithm is used to train the custom dataset and object detection is used to detect the fasteners. Region based convolutional neural networks (Faster R-CNN) uses a region proposed network (RPN) network to train the model efficiently and also with the help of Region of Interest able to localize the screw and nails objects with a mean average precision of 0.72 percent leads to accuracy of 95 percent object detectio

Study of Stromal Expression of CD 10 in Breast Carcinoma and Its Role as a Prognostic Marker

BACKGROUND : Breast carcinoma is the most common cancer among women, also tops the list of cancer death among women, living in under developed countries. The mortality of breast carcinoma is attributed to metastatic disease.CD10 is a 90-110 kD cell surface metalloproteinase, that may play a role in degrading extra cellular matrix and collagen, providing a microenvironment favourable for invasion and metastasis. AIM AND OBJECTIVES : 1. To study the stromal expression of CD 10 antigen in patients diagnosed as invasive ductal breast carcinoma by histopathological examination. 2. To study relationship with: 1. Age, 2. Menopausal status 3. Histologic subtypes 4.Nottingham’s grade and 3. Nottingham’s Prognostic index, 4. Mitotic rate and 5.Lymph node metastasis of the patients. MATERIALS AND METHODS : A total of 60 patients of breast cancer were included in the study. Representative sections were taken and Hematoxylin and Eosin staining was done. Immunohistochemistry was performed with CD10. Stromal expression of CD10 (10%-30% stromal positivity was considered weak positive, >30% as strong positive) in invasive breast carcinoma was noted and was statistically analysed. RESULTS : Stromal expression of CD10 was found to be significantly associated with increasing tumor grade (P = 0.047), Lymph node metastasis (P = 0.013) and Nottingham’s Prognostic index (P = 0.009). No correlation was found between CD10 expression and age, menopausal status, histologic subtypes, tumour size and mitotic rate. CONCLUSION : The stromal expression of CD10 has significant correlation with higher histological grade , lymph node metastasis, Nottingham’s prognostic index. There is no correlation between CD10 expression and age menopausal status, histologic subtypes, tumour size and mitotic rate. This study highlights the role of stromal CD10 expression in predicting tumor response and prognosis. Hence CD10 could be used as a prognostic marker

Effect of immunostimulant on enhancement of the immune response of kuruma shrimp Marsupenaeus japonicus and its resistance against White Spot Syndrome Virus (WSSV)

An experiment of 45 days duration to test the efficacy of the Vibrio alginolyticus as an immunostimulant was conducted in Marsupenaeus japonicus against white spot syndrome virus (WSSV) infection, considered as one of the serious pathogens of shrimps. The shrimps were fed with the experimental diets coated with different concentrations of bacteria of 17 ml / kg feed and 10 % of animal body wt. They were challenged with WSSV to assess the increase in survival rate and growth if any due to immune enhancement. Another group of shrimp was used for drawing the haemolymph to estimate the increase in the level of prophenoloxidase activity. Samplings for the above said analysis were carried out at 15 days interval for a period of 45 days. The highest prophenoloxidase activity (39.78 with sand substrate-T1) and the highest survival rate (66.66 % with sand substrate-T1) and highest growth rate (7.04 % in 17ml/kg- with sand substrate-T1) were recorded in experimental diet (17 ml / kg feed). Hence the 17 ml / kg feed of Vibrio alginolyticus formalin killed added to the diet could be an eco-friendly and economically viable immunostimulant for penaeid shrimps

A Study on Quality of Life (QOL) in Patients with Schizophrenia

BACKGROUND: Few studies have explored the Quality of Life among patients with schizophrenia In the treatment of schizophrenia the subjective quality of life is an important outcome. AIM OF THE STUDY: To determine the quality of life in patients with schizophrenia in Indian population, and to compare it with individuals without mental illness in general population. This study aimed to identify factors which influenced the quality of life in patients with schizophrenia. METHODOLOGY: This was a Cross sectional study in the Institute of Mental health- a Teaching institute and tertiary care referral centre involving WHOQOL-BREF questionnaire to evaluate the quality of life. Further Positive and negative syndrome scale, Calgary depressive scale for schizophrenia, Beck’s cognitive insight scale, WHODAS-II scale, UKU side effects scale, Social support questionnaire were all employed to study the psychopathology, insight, side effects and social support in the patient group. Descriptive statistics and tests of correlation, multivariate analysis using SPSS software-20 were performed. RESULTS: The quality of life in patients with schizophrenia was found to be lower than the individuals without mental illness. The variables which showed a strong association with quality of life in these patients were gender, age, employment, socio economic background, education, duration and phase of illness. Depression and negative symptoms had a strong correlation with quality of life. Disability and insight also influenced the quality of life. CONCLUSION: It was concluded that it is imperative to study the quality of life in patients with schizophrenia. Depressive and negative symptoms has to be catered to decrease lowering of quality of life. Early treatment and reduction of symptoms also is important an increased duration and active phase of illness causes a decline in quality of life. Disability prevention by early recovery and rehabilitation measures is very important to increase the treatment outcome and thereby the quality of life. The knowledge of these factors in these patients should be crucial to implement health policies and psychosocial rehabilitation programs focused on improving the quality of life of these patients

Design of Superconducting Spoke Cavities for High-Velocity Applications

Superconducting single- and multi-spoke cavities have been designed to-date for particle velocities from β0 ~ 0.15 to β0 ~ 0.65. Superconducting spoke cavities may also be of interest for higher-velocity, low-frequency applications, either for hadrons or electrons. We present the design of spoke cavities optimized for β0 = 0.8 and β0 = 1

Analysis of Higher Order Multipoles of the 952.6 Mhz RF-Dipole Crabbing Cavity for the Jefferson Lab Electron Ion Collider

The crabbing system is a key feature in the Jefferson Lab Electron-Ion Collider (JLEIC) required to increase the luminosity of the colliding bunches. A local crabbing system will be installed with superconducting rf-dipole crabbing cavities operating at 952.6 MHz. The field non-uniformity across the beam aperture in the crabbing cavities produces higher order multipole components, similar to that which are present in magnets. Knowledge of higher order mode multipole field effects is important for accurate beam dynamics study for the crabbing system. In this paper, we quantify the multipole components and analyse their effects on the beam dynamics

IN VITRO CYTOTOXICITY OF BIOSYNTHESIZED GOLD NANOPARTICLES FROM SHELLS OF PISTACIA VERA L

Objective: To synthesize the gold nanoparticles by a biological method using the extract obtained from the shells of Pistacia vera (P. vera) and to study its effective role in the anticancer activity.Methods: The synthesis of gold nanoparticles using the extract obtained from the shells of Pistacia vera was confirmed by the color change and substantiating the same using ultraviolet (UV) visible spectroscopy. The size and the shape of the particles were studied using field emission scanning electron microscopy (FESEM). The stability of the nanoparticles was assessed by using the UV visible spectroscopy and Fourier-transform infrared spectroscopy (FTIR). The anticancer activity of the gold nanoparticles on the cancer cell lines was studied on PA1 ovarian cancer cell lines using 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Nature of cell death was analyzed using the fluorescence microscopy.Results: The ruby red color confirmed the formation of gold nanoparticles and it was substantiated by the absorption peak at 543.2 nm in the UV visible spectroscopy. The gold nanoparticles synthesized from the Pistacia vera shell showed the spherical shape and were in the size of around 10-40 nm when analyzed with FESEM. The different functional groups were indicated in the FTIR spectra which were consisting of phenol, alcohol, alkenes and aromatics.Conclusion: The synthesis of the gold nanoparticle using the extract obtained from the shells of Pistacia vera has effective anticancer activity

2-Chloro­benzo[h]quinoline-3-carbaldehyde

The benzo[h]quinolinyl fused-ring of the title compound, C14H8ClNO, is planar (r.m.s. deviation = 0.016 Å); the formyl group is slightly bent out of the plane [the C—C—C—O torsion angle is 10.7 (4)°]